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Evidence by topic

How have eyes been observed around hyperbaric oxygen exposure?

140 papers. Randomized human trials: 4. Other comparative human studies: 13. Human observational studies and case reports: 117. Systematic reviews and meta analyses: 6.

Europe PMC MED and PMC title and abstract results were screened. Human research and systematic reviews containing human research have no lower publication year limit through 29 October 2026. Animal and cell original studies require a first publication date from 2024 onward. This abstract screened inventory covers the query results and is not a systematic review of all relevant literature. Counts refer to reports, with possible overlap of participants or studies across follow up reports and reviews. Groups are ordered by first publication date, newest first.

Checked 2026-10-29 · 230 records searched

Randomized human trials4

  1. Eighteen people with fibromyalgia were randomized to immediate hyperbaric oxygen or a 12 week waiting period; adverse events including myopia were assessed during eight weeks of exposure and three month follow up.

    Pain Med · 2021 · PMID 33594439

    DOI 10.1093/pm/pnaa416Record and abstract

  2. A randomized blinded hyperbaric oxygen versus placebo study in 50 diabetic foot patients assessed acuity, retinopathy and macular edema before exposure and at 3, 6, 12 and 24 months.

    Undersea Hyperb Med · 2020 · PMID 32931668

    DOI 10.22462/03.07.2020.3Record and abstract

  3. A randomized study of 48 people with retinitis pigmentosa compared hyperbaric oxygen and control, using scheduled 90 minute exposures at 2.2 atmospheres and annual eye examinations and electroretinography over three years.

    Doc Ophthalmol · 1998 · PMID 10710240

    DOI 10.1023/a:1002015317479Record and abstract

  4. A randomized trial of 40 people with chronic multiple sclerosis compared oxygen with control gas for 20 exposures of 90 minutes at 2 atmospheres, recording clinical scales and myopia and ear events.

    N Engl J Med · 1983 · PMID 6336824

    DOI 10.1056/nejm198301273080402Record and abstract

Other comparative human studies13

  1. Records of 15 central retinal artery occlusion patients compared seven receiving hyperbaric oxygen with eight receiving vitrectomy, analyzing acuity, intraocular pressure and timing.

    J Invest Surg · 2025 · PMID 40375561

    DOI 10.1080/08941939.2025.2503811Record and abstract

  2. A retrospective comparison assessed visual acuity in central retinal artery occlusion across 13 eyes with conservative care, 11 eyes from ten hyperbaric oxygen patients and ten surgically managed eyes.

    Int Ophthalmol · 2024 · PMID 39521754

    DOI 10.1007/s10792-024-03335-yRecord and abstract

  3. A study of 75 retinal artery occlusion patients compared visual acuity, neovascular glaucoma and stroke records between 27 hyperbaric oxygen recipients and nonrecipients.

    Retina · 2024 · PMID 39163734

    DOI 10.1097/iae.0000000000004253Record and abstract

  4. A study of 55 adults with carbon monoxide poisoning measured optic nerve sheath diameter by ocular ultrasound, comparing values before and six hours after normobaric or hyperbaric oxygen.

    P R Health Sci J · 2021 · PMID 35077077

    Record and abstract

  5. A registry study of 19 central retinal artery occlusion patients compared acuity changes in ten receiving adjunctive hyperbaric oxygen and those without it.

    Undersea Hyperb Med · 2020 · PMID 32176947

    DOI 10.22462/01.03.2020.7Record and abstract

  6. A prospective comparison of 50 people with nonproliferative diabetic retinopathy included 25 hyperbaric oxygen recipients and 25 nonrecipients, measuring acuity, pressure, fundus and OCT around 30 sessions.

    J Fr Ophtalmol · 2019 · PMID 31831276

    DOI 10.1016/j.jfo.2019.07.005Record and abstract

  7. Sixteen phakic and six pseudophakic patients receiving hyperbaric oxygen underwent eye examinations across 19 days, measuring refraction, lens, cornea and pressure.

    Optom Vis Sci · 2011 · PMID 21399553

    DOI 10.1097/opx.0b013e318213f001Record and abstract

  8. A 21 day hyperbaric oxygen study compared refraction in 20 mask and 12 hood users, with follow up to ten weeks and lens opacity measurements in a subgroup.

    Acta Ophthalmol Scand · 2004 · PMID 15291940

    DOI 10.1111/j.1395-3907.2004.00290.xRecord and abstract

  9. A comparison of acute retinal artery occlusion included 18 hyperbaric oxygen recipients and 14 nonrecipients, with conventional measures in both groups and acuity followed for three months.

    Ophthalmologe · 2000 · PMID 10959180

    DOI 10.1007/s003470070075Record and abstract

  10. Seven diabetic neuropathy patients, three diabetic patients without neuropathy and seven healthy controls received hyperbaric oxygen, with ophthalmic artery velocity measured before and after by color Doppler.

    Jpn J Ophthalmol · 1998 · PMID 9822973

    DOI 10.1016/s0021-5155(98)00029-xRecord and abstract

  11. Ophthalmic artery Doppler was recorded around hyperbaric oxygen in seven diabetic neuropathy patients, three other diabetic patients and seven healthy controls; participants may overlap with the later English report.

    Nippon Ganka Gakkai Zasshi · 1997 · PMID 9311233

    Record and abstract

  12. Eight hyperbaric oxygen recipients underwent serial refraction, acuity and blood oxidation measurements; four received placebo followed sequentially by antioxidant supplements.

    Optom Vis Sci · 1996 · PMID 8843129

    DOI 10.1097/00006324-199607000-00006Record and abstract

  13. A study compared lens nuclear vacuoles in 25 hyperbaric oxygen recipients and 100 preoperative senile nuclear cataract patients using slit lamp photography and microradiography.

    Acta Ophthalmol (Copenh) · 1986 · PMID 3962621

    DOI 10.1111/j.1755-3768.1986.tb06873.xRecord and abstract

Human observational studies and case reports117

  1. A retrospective series of 11 ocular or eyelid reconstruction patients compared postoperative course and cultures across records of 10 or 20 hyperbaric oxygen sessions.

    Int Ophthalmol · 2026 · PMID 42837034

    DOI 10.1007/s10792-026-04286-2Record and abstract

  2. One man with macular edema after cataract surgery received ophthalmic medication and 11 hyperbaric oxygen sessions; visual acuity and retinal thickness on OCT were followed.

    Orv Hetil · 2026 · PMID 42437467

    DOI 10.1556/650.2026.33555Record and abstract

  3. One woman with Cogan syndrome received infliximab, methotrexate and hyperbaric oxygen; ocular symptoms including keratitis were followed alongside hearing.

    Eur J Case Rep Intern Med · 2026 · PMID 42466223

    DOI 10.12890/2026_007109Record and abstractFree full text

  4. One man with central retinal artery occlusion after cervical surgery received 14 hyperbaric oxygen sessions at 2 atmospheres; acuity, visual field and retinal imaging were observed.

    BMC Anesthesiol · 2026 · PMID 42363062

    DOI 10.1186/s12871-026-04043-zRecord and abstractFree full text

  5. One woman with emphysema and pupillary and accommodation abnormalities after hip surgery received four hyperbaric oxygen sessions; near and distance vision and pupillary responses were followed.

    J Clin Med · 2026 · PMID 42355802

    DOI 10.3390/jcm15124634Record and abstractFree full text

  6. One woman receiving hyperbaric oxygen for retinal artery occlusion also had a choroidal lesion in the other eye observed; bilateral acuity and OCT were recorded.

    Diving Hyperb Med · 2026 · PMID 42290581

    DOI 10.28920/dhm56.2.195-197Record and abstract

  7. One man with retinal arterial and venous occlusion after transfusion received anticoagulation and hyperbaric oxygen; fundus, OCT and acuity were followed.

    Case Rep Ophthalmol · 2026 · PMID 41835312

    DOI 10.1159/000550754Record and abstractFree full text

  8. One man with central retinal artery occlusion received hyperbaric oxygen within 48 hours of presentation; acuity, fundus, OCT and adverse events were recorded.

    Ther Adv Ophthalmol · 2026 · PMID 41573420

    DOI 10.1177/25158414251405382Record and abstractFree full text

  9. A retrospective cohort grouped 101 eyes with central retinal artery occlusion by hyperbaric oxygen timing and measured acuity and OCT retinal thickness at presentation, one week and six months.

    Undersea Hyperb Med · 2026 · PMID 42826426

    Record and abstract

  10. A branch retinal artery occlusion case series followed visual acuity after hyperbaric oxygen begun at 5, 36 or 48 hours; total sample size was not explicitly stated in the abstract.

    Cureus · 2025 · PMID 41399591

    DOI 10.7759/cureus.96804Record and abstractFree full text
Show all · 117 papersShow less

  1. An emergency department case followed visual acuity for three months in one woman receiving hyperbaric oxygen for central retinal artery occlusion.

    Cureus · 2025 · PMID 41376755

    DOI 10.7759/cureus.96423Record and abstractFree full text

  2. Twenty patients with hearing loss or avascular necrosis underwent eye examinations, electroretinography and OCT before and within 24 hours of their first hyperbaric oxygen session.

    Front Ophthalmol (Lausanne) · 2025 · PMID 41190089

    DOI 10.3389/fopht.2025.1652282Record and abstractFree full text

  3. A prospective series collected acuity, OCT and fluorescein angiography around hyperbaric oxygen in 26 central retinal artery occlusion patients, with mean follow up of ten months.

    World J Methodol · 2025 · PMID 40548218

    DOI 10.5662/wjm.v15.i2.96777Record and abstractFree full text

  4. Two patients with vision loss after ear filler received thrombolysis, medication and hyperbaric oxygen; ophthalmic artery angiography and vision were observed.

    Aesthetic Plast Surg · 2025 · PMID 40346341

    DOI 10.1007/s00266-025-04881-1Record and abstract

  5. Corneal thickness, anterior chamber depth and volumes were measured before and after hyperbaric oxygen in 92 patients with nonocular conditions, also comparing 22 diabetic and 70 nondiabetic participants.

    Cutan Ocul Toxicol · 2025 · PMID 40272842

    DOI 10.1080/15569527.2025.2496640Record and abstract

  6. One woman with ocular ischemia and central retinal artery occlusion after filler injection received ocular massage, aflibercept and hyperbaric oxygen; vision was observed.

    J Cosmet Laser Ther · 2025 · PMID 40091289

    DOI 10.1080/14764172.2025.2478142Record and abstract

  7. A three person case series observed visual and orbital tissue course after adjunctive hyperbaric oxygen for conditions associated with orbital surgery, fillers or trauma.

    J Fr Ophtalmol · 2024 · PMID 39674097

    DOI 10.1016/j.jfo.2024.104382Record and abstract

  8. One diver receiving hyperbaric oxygen after decompression sickness was followed for pigment epithelial detachment and scotoma using OCT, angiography and acuity over three months.

    Am J Ophthalmol Case Rep · 2024 · PMID 39649384

    DOI 10.1016/j.ajoc.2024.102208Record and abstractFree full text

  9. One man with cilioretinal artery occlusion after cataract and macular hole surgery received medication and 20 hyperbaric oxygen sessions; acuity, OCT and angiography were observed.

    Eur J Ophthalmol · 2024 · PMID 39435512

    DOI 10.1177/11206721241290268Record and abstract

  10. One woman with ophthalmic artery embolization after ear filler received vascular intervention, medication and hyperbaric oxygen; light perception and ocular course were recorded.

    Aesthetic Plast Surg · 2024 · PMID 39174801

    DOI 10.1007/s00266-024-04327-0Record and abstract

  11. A retrospective study of 114 adults receiving 90 minute hyperbaric oxygen sessions at 2.4 atmospheres for central retinal artery occlusion analyzed acuity, adverse events and session counts.

    Cureus · 2024 · PMID 39113814

    DOI 10.7759/cureus.66196Record and abstractFree full text

  12. A prospective study of 31 retinal artery occlusion patients used twice daily 90 minute hyperbaric oxygen sessions at 2.5 atmospheres, following acuity, angiography, OCT and adverse events.

    Br J Ophthalmol · 2024 · PMID 37722767

    DOI 10.1136/bjo-2023-323972Record and abstractFree full text

  13. One woman with vision loss after filler injection received hyaluronidase, ocular massage and three hyperbaric oxygen sessions; subsequent acuity was recorded.

    Aesthet Surg J Open Forum · 2024 · PMID 38863892

    DOI 10.1093/asjof/ojae036Record and abstractFree full text

  14. A case recorded vision loss and ocular diagnosis in one woman who began hyperbaric oxygen within six hours of central retinal artery occlusion after thyroid surgery.

    Acta Chir Belg · 2024 · PMID 38391299

    DOI 10.1080/00015458.2024.2323286Record and abstract

  15. One woman with vision loss after ear filler received hyaluronidase, medication and hyperbaric oxygen; ophthalmic arterial flow and acuity were recorded.

    Aesthetic Plast Surg · 2024 · PMID 38388798

    DOI 10.1007/s00266-024-03903-8Record and abstract

  16. An online survey analyzed 265 healthcare provider responses on hyperbaric oxygen pressures, conditions and reported adverse events including myopia.

    Undersea Hyperb Med · 2024 · PMID 39821765

    DOI 10.22462/680Record and abstract

  17. One child with odontogenic orbital cellulitis received drainage, antibiotics, steroids and hyperbaric oxygen; acuity and orbital imaging were followed.

    Optom Vis Sci · 2023 · PMID 37639550

    DOI 10.1097/opx.0000000000002062Record and abstractFree full text

  18. Seventeen eyes of 17 patients with nonocular conditions were examined before, after one and after 20 hyperbaric oxygen sessions for endothelial structure, pressure, refraction, axial length and chamber depth.

    Cutan Ocul Toxicol · 2023 · PMID 37531136

    DOI 10.1080/15569527.2023.2243499Record and abstract

  19. One man with maculopathy after cataract surgery received 14 hyperbaric oxygen sessions; OCT and acuity were followed.

    Photodiagnosis Photodyn Ther · 2023 · PMID 37454919

    DOI 10.1016/j.pdpdt.2023.103714Record and abstract

  20. A prospective study measured acuity, fundus and electroretinography before and after ten hyperbaric oxygen sessions in 40 eyes of 20 patients with nonocular conditions.

    Cutan Ocul Toxicol · 2023 · PMID 37221823

    DOI 10.1080/15569527.2023.2217250Record and abstract

  21. A retrospective study reviewed 774 courses of wound care and hyperbaric oxygen, recording wounds, quality of life and adverse events including myopia.

    Adv Skin Wound Care · 2023 · PMID 37017408

    DOI 10.1097/01.asw.0000922696.61546.31Record and abstract

  22. One woman with endophthalmitis and orbital cellulitis received evisceration, debridement, antibiotics and hyperbaric oxygen; conjunctival and scleral course was recorded.

    Rom J Ophthalmol · 2023 · PMID 37522028

    DOI 10.22336/rjo.2023.33Record and abstractFree full text

  23. One woman with multiple branch retinal artery occlusions after filler injection received medication, acupuncture and 40 hyperbaric oxygen sessions; acuity was followed for two months.

    BMC Ophthalmol · 2023 · PMID 36879205

    DOI 10.1186/s12886-023-02821-8Record and abstractFree full text

  24. A study of 38 hyperbaric oxygen recipients with nonarteritic central retinal artery occlusion analyzed exposure timing and acuity before and at follow up.

    Undersea Hyperb Med · 2023 · PMID 37708058

    Record and abstract

  25. One man with maculopathy and cilioretinal artery occlusion received hyperbaric oxygen with interval normobaric oxygen; serial visual field and retinal examinations followed the course.

    Undersea Hyperb Med · 2023 · PMID 37708061

    DOI 10.22462/01.01.2023.9Record and abstract

  26. One woman with Stevens Johnson syndrome received ocular surface graft surgery and 17 hyperbaric oxygen sessions; corneal and conjunctival graft course and acuity were recorded.

    Heliyon · 2022 · PMID 36820177

    DOI 10.1016/j.heliyon.2022.e12590Record and abstractFree full text

  27. One person with vision loss after forehead fat injection received medication and hyperbaric oxygen; fluorescein angiography and acuity were followed for 24 months.

    J Fr Ophtalmol · 2022 · PMID 35718568

    DOI 10.1016/j.jfo.2022.03.005Record and abstract

  28. OCT in right eyes of 35 patients with nonocular conditions measured macular, nerve fiber layer and choroidal thickness and vascularity before and after one and 20 hyperbaric oxygen sessions.

    Photodiagnosis Photodyn Ther · 2022 · PMID 35390520

    DOI 10.1016/j.pdpdt.2022.102854Record and abstract

  29. A cohort of 1,005 breast cancer patients receiving hyperbaric oxygen for late radiation symptoms recorded questionnaires and adverse events including myopia before, after and at three months.

    Breast Cancer Res Treat · 2021 · PMID 34279734

    DOI 10.1007/s10549-021-06332-2Record and abstractFree full text

  30. One man with orbital and cerebral fungal infection received antifungals, surgery and 30 hyperbaric oxygen sessions; imaging and long term neurological and ocular status including eyelid closure were recorded.

    Proc (Bayl Univ Med Cent) · 2021 · PMID 34732994

    DOI 10.1080/08998280.2021.1935138Record and abstractFree full text

  31. One woman with retinal artery occlusion after temple filler received massage, eye drops and hyperbaric oxygen; fundus, OCT, angiography and acuity were observed.

    Taiwan J Ophthalmol · 2021 · PMID 34703751

    DOI 10.4103/tjo.tjo_9_21Record and abstractFree full text

  32. One child with leukemia and orbital cerebral fungal infection received antifungals, hyperbaric oxygen and surgery including orbital exenteration; imaging and ocular and systemic course were recorded.

    Am J Ophthalmol Case Rep · 2021 · PMID 34095606

    DOI 10.1016/j.ajoc.2021.101092Record and abstractFree full text

  33. One woman with ophthalmic artery occlusion after filler received pressure lowering medication, massage, anticoagulation and hyperbaric oxygen, with fundus, OCT, angiography and MRI observations.

    Ann Plast Surg · 2021 · PMID 33346533

    DOI 10.1097/sap.0000000000002624Record and abstract

  34. One woman with retinal arterial and venous occlusion after hormonal exposure received 30 two hour hyperbaric oxygen sessions at 2.5 atmospheres; fundus, angiography and acuity were observed.

    Diving Hyperb Med · 2020 · PMID 33325028

    DOI 10.28920/dhm50.4.431-436Record and abstractFree full text

  35. One woman with optic neuropathy after valproate overdose received hyperbaric oxygen and neurological medications for four months; acuity, fields and optic nerve examinations were followed.

    Eur J Ophthalmol · 2020 · PMID 33222509

    DOI 10.1177/1120672120974943Record and abstract

  36. Three central retinal artery occlusion cases distinguished thrombolysis and hyperbaric oxygen; two received four and 12 oxygen sessions respectively, with acuity and imaging recorded.

    J Thromb Thrombolysis · 2020 · PMID 32166539

    DOI 10.1007/s11239-020-02072-0Record and abstract

  37. Four patients receiving acute hyperbaric oxygen for central retinal artery occlusion were followed for visual acuity, retinal structure and neovascular complications.

    J Vitreoretin Dis · 2020 · PMID 37009086

    DOI 10.1177/2474126420951989Record and abstractFree full text

  38. One man with central retinal artery occlusion after spinal surgery received medication, fluids and hyperbaric oxygen; postoperative acuity was followed.

    J Int Med Res · 2020 · PMID 32883134

    DOI 10.1177/0300060520952279Record and abstractFree full text

  39. One man with diabetic retinopathy and branch retinal artery occlusion after high altitude exposure received hyperbaric oxygen; acuity, fields and retina were examined before and after.

    BMC Ophthalmol · 2020 · PMID 32652960

    DOI 10.1186/s12886-020-01563-1Record and abstractFree full text

  40. A series of 30 radiation tissue injury patients receiving adjunctive hyperbaric oxygen recorded wound course and complications including myopia.

    Indian J Surg Oncol · 2020 · PMID 33013130

    DOI 10.1007/s13193-020-01128-0Record and abstractFree full text

  41. A case recorded the diagnostic course and ocular symptoms of one male diver who received hyperbaric oxygen for blurred vision and vertigo before identification of a sphenoid sinus mucocele.

    Diving Hyperb Med · 2020 · PMID 32557420

    DOI 10.28920/dhm50.2.168-172Record and abstractFree full text

  42. One man with maculopathy after inhaled nitrite exposure received ten days of hyperbaric oxygen; acuity, OCT, autofluorescence and OCT angiography were recorded.

    GMS Ophthalmol Cases · 2020 · PMID 32676261

    DOI 10.3205/oc000143Record and abstractFree full text

  43. One man with anomalous retinal artery and branch occlusion received medication, massage and hyperbaric oxygen; initial imaging and acuity, later telephone follow up and glaucoma records were assessed.

    World J Clin Cases · 2020 · PMID 32190636

    DOI 10.12998/wjcc.v8.i5.980Record and abstractFree full text

  44. One woman with radiation optic neuropathy received steroids, bevacizumab and 19 hyperbaric oxygen sessions; acuity and optic nerve MRI were recorded.

    BMJ Case Rep · 2020 · PMID 32107259

    DOI 10.1136/bcr-2019-233706Record and abstractFree full text

  45. A retrospective series of 16 orbital emphysema cases after vitreoretinal surgery analyzed compression, drainage, surgery and hyperbaric oxygen records, CT and final acuity.

    Ophthalmol Retina · 2020 · PMID 32192937

    DOI 10.1016/j.oret.2020.01.008Record and abstract

  46. One woman with keratitis and visual changes after facial filler injection received hyperbaric oxygen; the ocular course was recorded.

    Ochsner J · 2020 · PMID 32612475

    DOI 10.31486/toj.18.0133Record and abstractFree full text

  47. Eleven people with nonarteritic central retinal artery occlusion had acuity and eye examinations around hyperbaric oxygen and thrombophilia variants recorded.

    Undersea Hyperb Med · 2020 · PMID 32176948

    DOI 10.22462/01.03.2020.8Record and abstract

  48. A case recorded bilateral lens opacity and visual changes at 46 sessions in one woman receiving hyperbaric oxygen for a postradiation leg wound.

    Mo Med · 2019 · PMID 31645792

    Record and abstractFree full text

  49. One woman with posterior ischemic optic neuropathy after angiography received steroids and hyperbaric oxygen; serial ophthalmic visits observed vision.

    Undersea Hyperb Med · 2019 · PMID 31683370

    DOI 10.22462/10.12.2019.16Record and abstract

  50. A conference case report described three patients with radiation optic neuropathy, recording timing of multiple interventions including hyperbaric oxygen and visual and MRI course.

    Neuro Oncol · 2019 · PMCID PMC6795115

    Record and abstractFree full text

  51. A retrospective study of 28 central retinal artery occlusion patients analyzed hyperbaric oxygen session counts, acuity and inner retinal OCT structure.

    Int J Ophthalmol · 2019 · PMID 31236358

    DOI 10.18240/ijo.2019.06.18Record and abstractFree full text

  52. A case described hyperbaric oxygen in one patient with central retinal and carotid artery occlusion, recording vision loss, vascular assessment and subsequent course.

    Clin Pract Cases Emerg Med · 2019 · PMID 31403098

    DOI 10.5811/cpcem.2019.4.40847Record and abstractFree full text

  53. A retrospective surgical series of 21 pituitary apoplexy patients recorded postoperative adjunctive hyperbaric oxygen and endocrine and neuro ophthalmic course.

    Pituitary · 2019 · PMID 30390276

    DOI 10.1007/s11102-018-0922-2Record and abstract

  54. Twenty nine patients receiving 40 hyperbaric oxygen sessions had refraction and acuity assessed every ten sessions and at 12 weeks; 19 underwent additional examinations including lens opacity.

    Acta Ophthalmol · 2019 · PMID 30690920

    DOI 10.1111/aos.14010Record and abstract

  55. One woman with central retinal artery occlusion received three hyperbaric oxygen sessions at 2.8 atmospheres over three days; near and distance acuity were observed.

    Clin Exp Emerg Med · 2018 · PMID 30571907

    DOI 10.15441/ceem.17.271Record and abstractFree full text

  56. Twenty three patients receiving hyperbaric oxygen for six weeks underwent twice weekly measurements of refraction, corneal parameters and intraocular pressure immediately before and after sessions.

    Undersea Hyperb Med · 2018 · PMID 30241118

    DOI 10.22462/07.08.2018.3Record and abstract

  57. Ten central retinal artery occlusion patients received medication and 20 hyperbaric oxygen sessions; acuity was assessed after sessions and neovascular glaucoma observed.

    Undersea Hyperb Med · 2018 · PMID 30241121

    DOI 10.22462/07.08.2018.6Record and abstract

  58. One man with ophthalmic artery occlusion and hemiparesis after diving received seven hyperbaric sessions; visual and neurological course and MR angiography were recorded.

    Diving Hyperb Med · 2018 · PMID 29888385

    DOI 10.28920/dhm48.2.112-113Record and abstractFree full text

  59. One woman with retinal arterial spasm after septoplasty received massage, paracentesis and hyperbaric oxygen; pupil, fundus and visual course were observed.

    J Craniofac Surg · 2018 · PMID 29239920

    DOI 10.1097/scs.0000000000004202Record and abstract

  60. A retrospective review of 31 acute retinal artery occlusion cases extracted time to hyperbaric oxygen, acuity, session counts and adverse events.

    Diving Hyperb Med · 2017 · PMID 29241233

    DOI 10.28920/dhm47.4.233-238Record and abstractFree full text

  61. A case recorded retinal examinations before and after five and 17 hyperbaric oxygen sessions in one man with diabetic foot ulcers, describing fundus, acuity and accompanying retinal procedures.

    Diving Hyperb Med · 2017 · PMID 28868603

    DOI 10.28920/dhm47.3.203Record and abstractFree full text

  62. Two patients with central retinal artery occlusion received eight and nine hyperbaric oxygen sessions at 2.4 atmospheres, with acuity and fluorescein angiography compared over time.

    BMJ Case Rep · 2017 · PMID 28500127

    DOI 10.1136/bcr-2017-220113Record and abstractFree full text

  63. One man with branch retinal artery occlusion received medication and hyperbaric oxygen followed by vitrectomy and retinal vascular procedures; acuity, fundus and OCT were followed.

    Indian J Ophthalmol · 2017 · PMID 28513500

    DOI 10.4103/ijo.ijo_698_16Record and abstractFree full text

  64. One woman with conjunctival graft compromise after pterygium surgery received eye drops and hyperbaric oxygen with interruption of anti VEGF injections; scleral course was observed.

    Cornea · 2016 · PMID 27749445

    DOI 10.1097/ico.0000000000001035Record and abstract

  65. A report described one retinal arterial and venous occlusion patient receiving daily two hour hyperbaric oxygen at 2.5 atmospheres for 14 days, with visual acuity observed alongside a literature discussion.

    J Craniofac Surg · 2016 · PMID 28005776

    DOI 10.1097/scs.0000000000003089Record and abstract

  66. A case observed ocular neovascularization within one month after hyperbaric oxygen in one patient with central retinal artery occlusion.

    Ophthalmol Ther · 2016 · PMID 27613631

    DOI 10.1007/s40123-016-0064-4Record and abstractFree full text

  67. One woman with posterior ciliary artery occlusion after forehead filler received hyaluronidase, medication and hyperbaric oxygen; fundus angiography and acuity were observed.

    Medicine (Baltimore) · 2016 · PMID 26986163

    DOI 10.1097/md.0000000000003124Record and abstractFree full text

  68. Lens imaging, refraction, cornea, pressure and axial length were compared on day one and after 19 days of hyperbaric oxygen; sample size was not stated in the abstract.

    Optom Vis Sci · 2015 · PMID 26414557

    DOI 10.1097/opx.0000000000000705Record and abstract

  69. One woman with congenital cardiac abnormalities and central retinal artery occlusion received massage, paracentesis, aspirin and hyperbaric oxygen; fundus and echocardiographic assessment were recorded.

    BMC Ophthalmol · 2015 · PMID 26481874

    DOI 10.1186/s12886-015-0126-8Record and abstractFree full text

  70. One woman with retinal arterial and venous occlusion received nine hyperbaric oxygen sessions over seven days and subsequent bevacizumab; acuity and angiography were followed for ten months.

    Case Rep Ophthalmol · 2015 · PMID 26955350

    DOI 10.1159/000442788Record and abstractFree full text

  71. One male diver with bilateral ophthalmoplegia received hyperbaric oxygen; eye movements, neurological course and diving equipment records were reviewed.

    Undersea Hyperb Med · 2015 · PMID 26403021

    Record and abstract

  72. A retrospective study analyzed 189 of 276 radiation tissue injury patients with follow up data, recording complications after hyperbaric oxygen including ocular barotrauma.

    Asia Pac J Clin Oncol · 2014 · PMID 25382755

    DOI 10.1111/ajco.12289Record and abstract

  73. Fifteen patients had retinal thickness and structure, pulsatile ocular blood flow, refraction and axial length measured before and after 19 days of hyperbaric oxygen.

    Undersea Hyperb Med · 2014 · PMID 25562950

    Record and abstract

  74. One woman with ophthalmic artery occlusion after glabellar filler received massage, hyperbaric oxygen and urokinase; angiography, electroretinography and acuity were recorded.

    Nippon Ganka Gakkai Zasshi · 2014 · PMID 25318187

    Record and abstract

  75. A prospective hyperbaric oxygen study in 44 pelvic radiation injury patients recorded symptom scales, discontinuation and adverse events including transient myopia.

    Gastroenterol Res Pract · 2014 · PMID 24592276

    DOI 10.1155/2014/108073Record and abstractFree full text

  76. One woman with branch retinal artery occlusion received ten hyperbaric oxygen sessions over 20 days, with acuity, fields and fundus followed for four months.

    Diving Hyperb Med · 2013 · PMID 24122193

    Record and abstract

  77. Nine nasopharyngeal cancer patients with radiation optic neuropathy were reviewed for steroid, anticoagulation and hyperbaric oxygen exposure, eye examinations, acuity and MRI.

    J Clin Neurosci · 2013 · PMID 23317755

    DOI 10.1016/j.jocn.2012.05.034Record and abstract

  78. A retrospective review of 61 eyes in 35 radiation optic neuropathy patients recorded multiple approaches including hyperbaric oxygen, steroids and laser, with acuity, fields, fundus and evoked potentials.

    Zhonghua Yan Ke Za Zhi · 2011 · PMID 22336114

    Record and abstract

  79. One patient with prior optic neuritis received 40 hyperbaric oxygen sessions with comprehensive eye examinations before and after.

    Undersea Hyperb Med · 2011 · PMID 22292261

    Record and abstract

  80. Forty four eyes of diabetic patients underwent automated refraction every ten sessions across 30 hyperbaric oxygen exposures, recording spherical and cylindrical power and axis.

    Harefuah · 2010 · PMID 21916099

    Record and abstract

  81. A two case report recorded acuity after central retinal artery occlusion following cataract surgery; hyperbaric oxygen and pressure lowering measures were explicitly described for the first woman.

    Retin Cases Brief Rep · 2010 · PMID 25390678

    DOI 10.1097/icb.0b013e3181ae7181Record and abstract

  82. One diver receiving hyperbaric oxygen after decompression sickness was followed for 18 months with acuity, fields, angiography, OCT and electroretinography.

    Retin Cases Brief Rep · 2010 · PMID 25390671

    DOI 10.1097/icb.0b013e3181a3b9d6Record and abstract

  83. One child with diabetes and orbital cerebral fungal infection was followed for 30 months through hyperbaric oxygen, surgery and multiple antifungals, recording ocular swelling, pain and infection course.

    Pediatr Diabetes · 2009 · PMID 18828793

    DOI 10.1111/j.1399-5448.2008.00465.xRecord and abstract

  84. One man with retinal embolization after carotid intervention received antiplatelet medication and one week of hyperbaric oxygen; acuity and fields were followed.

    Neurol Med Chir (Tokyo) · 2009 · PMID 19465793

    DOI 10.2176/nmc.49.213Record and abstract

  85. A man receiving hyperbaric oxygen after dichloromethane exposure had optic nerve status followed using acuity, fields, flicker threshold, electroretinography and evoked potentials.

    J Ocul Pharmacol Ther · 2008 · PMID 19049266

    DOI 10.1089/jop.2007.0100Record and abstract

  86. One woman with osteomyelitis received 48 hyperbaric oxygen sessions at 2.5 atmospheres; refraction and lens examinations were compared before exposure and eight weeks after completion.

    Undersea Hyperb Med · 2007 · PMID 18251434

    Record and abstract

  87. One woman with ophthalmic artery occlusion after glabellar fat injection received urokinase, hyperbaric oxygen and steroids; fundus and retinal and cerebral angiography were recorded.

    Nippon Ganka Gakkai Zasshi · 2007 · PMID 17305092

    Record and abstract

  88. One woman with radiation optic neuropathy received hyperbaric oxygen after steroids, with serial visual field and optic nerve and chiasm MRI assessment.

    Eur J Endocrinol · 2006 · PMID 16728540

    DOI 10.1530/eje.1.02161Record and abstract

  89. A case followed bilateral refraction for 1.5 years in one man receiving two hyperbaric oxygen courses, recording myopic and hyperopic measurements.

    Optom Vis Sci · 2006 · PMID 16534462

    DOI 10.1097/01.opx.0000204527.01889.e9Record and abstract

  90. Three hyperbaric oxygen recipients had fundus photographs on multiple days of a 30 session course, measuring retinal vessel diameter, pulse and blood pressure.

    Br J Ophthalmol · 2004 · PMID 15148210

    DOI 10.1136/bjo.2003.018788Record and abstractFree full text

  91. One man with iron deficiency anemia and branch retinal artery occlusion received nerve blockade, iron and hyperbaric oxygen; acuity, fundus and fluorescein angiography were observed.

    Tohoku J Exp Med · 2004 · PMID 15212150

    DOI 10.1620/tjem.203.141Record and abstract

  92. One woman with orbital and cavernous sinus fungal infection received amphotericin and hyperbaric oxygen; ocular movement, visual symptoms and MRI course were described.

    Rev Neurol (Paris) · 2003 · PMID 14978421

    Record and abstract

  93. Among 26 hyperbaric oxygen enrollees, 17 had refraction, corneal and axial measurements before and after 20 sessions; 13 also attended postcourse examinations.

    Acta Ophthalmol Scand · 2002 · PMID 11952487

    DOI 10.1034/j.1600-0420.2002.800213.xRecord and abstract

  94. One patient with scleral necrosis after pterygium surgery and mitomycin received 24 hyperbaric oxygen sessions; scleral thickness and vascular status were observed.

    Ophthalmic Surg Lasers · 2002 · PMID 11820665

    DOI 10.3928/1542-8877-20020101-11Record and abstract

  95. Two patients with nonarteritic anterior ischemic optic neuropathy received hyperbaric oxygen at 2 atmospheres; acuity and fields were observed over three to five months.

    Undersea Hyperb Med · 2002 · PMID 12508973

    Record and abstract

  96. A report recorded 24 hyperbaric oxygen sessions and ocular course in one patient with scleral necrosis after pterygium surgery and mitomycin; the case may overlap with another bibliographic record bearing the same title.

    Ophthalmic Surg Lasers · 2001 · PMID 11725777

    Record and abstract

  97. One patient with orbital fungal infection received surgery, systemic and orbital antifungals and hyperbaric oxygen; acuity, ocular function and infection course were recorded.

    Ophthalmic Plast Reconstr Surg · 2001 · PMID 11206749

    DOI 10.1097/00002341-200101000-00012Record and abstract

  98. One diabetic man with fungal scleritis after cataract surgery received amphotericin and hyperbaric oxygen; enucleated globe histology and one year course were recorded.

    J Cataract Refract Surg · 1998 · PMID 9584256

    DOI 10.1016/s0886-3350(98)80302-7Record and abstract

  99. Two people with visual loss after quinine exposure received charcoal followed by hyperbaric oxygen at 2.4 atmospheres; acuity, pupils and fields were followed.

    Undersea Hyperb Med · 1997 · PMID 9171472

    Record and abstract

  100. Healthy volunteers aged ten to 50 underwent contrast sensitivity testing before and after 60 minutes of hyperbaric oxygen at 2.5 atmospheres; participant count was not stated in the abstract.

    Undersea Hyperb Med · 1994 · PMID 8000278

    Record and abstract

  101. Three patients with postcataract endophthalmitis received intraocular procedures and antibiotics, with one also receiving hyperbaric oxygen; acuity, inflammation and possible ocular toxicity were recorded.

    Ophthalmic Surg · 1993 · PMID 8321509

    DOI 10.3928/1542-8877-19930401-09Record and abstract

  102. One patient with orbital pyoderma gangrenosum received hyperbaric oxygen before and after evisceration; orbital and ocular lesions were followed.

    Eye (Lond) · 1993 · PMID 8325431

    DOI 10.1038/eye.1993.19Record and abstract

  103. One man with bilateral orbital cerebral fungal infection received exenteration, amphotericin and hyperbaric oxygen; initial vision, eye movement and 1.5 year course were recorded.

    Am J Ophthalmol · 1992 · PMID 1642297

    DOI 10.1016/s0002-9394(14)73986-8Record and abstract

  104. One patient with anterior segment ischemia after strabismus surgery received hyperbaric oxygen; acute ocular symptoms were observed.

    Can J Ophthalmol · 1987 · PMID 3435855

    Record and abstract

  105. A case observed the course of bilateral central scotoma after hyperbaric oxygen in one woman with multiple sclerosis.

    J Fr Ophtalmol · 1987 · PMID 3598057

    Record and abstract

  106. Twenty five patients receiving at least 150 hyperbaric oxygen exposures underwent examinations before, during and after the course for refraction, lens opacity and acuity.

    Br J Ophthalmol · 1984 · PMID 6691953

    DOI 10.1136/bjo.68.2.113Record and abstractFree full text

  107. A series examined refraction and other ocular findings in 26 patients receiving hyperbaric oxygen for more than one month.

    Trans Ophthalmol Soc U K (1962) · 1978 · PMID 285513

    Record and abstract

Systematic reviews and meta analyses6

  1. A systematic search selected 35 reports of neuro ophthalmic vascular occlusion after fillers and combined them with expert consensus, covering multiple approaches including hyperbaric oxygen.

    Aesthetic Plast Surg · 2026 · PMID 41840246

    DOI 10.1007/s00266-026-05792-5Record and abstract

  2. A systematic review of 42 hyperbaric oxygen studies involving 2,785 radiotherapy patients extracted clinical measures and adverse event reports including transient myopia.

    Support Care Cancer · 2026 · PMID 41627499

    DOI 10.1007/s00520-026-10323-8Record and abstract

  3. An evidence review selected 19 studies with 198 cases of filler related vision loss using defined criteria, covering multiple interventions including hyperbaric oxygen and ocular course.

    Ophthalmology · 2025 · PMID 40167411

    DOI 10.1016/j.ophtha.2025.01.020Record and abstract

  4. A systematic review searched three databases for hyperbaric oxygen or diving and refractive changes, selecting 22 papers and describing an additional diver case.

    Diving Hyperb Med · 2024 · PMID 39675741

    DOI 10.28920/dhm54.4.328-337Record and abstractFree full text

  5. A systematic review selected 67 ocular adverse event reports from four databases in multiple sclerosis, combining 11 experimental and 56 observational reports of multiple interventions including hyperbaric oxygen.

    Syst Rev · 2021 · PMID 34711264

    DOI 10.1186/s13643-021-01782-7Record and abstractFree full text

  6. A systematic review combined 22 reports with 117 traumatic orbital apex syndrome patients, analyzing acuity and eye movement records across approaches including hyperbaric oxygen.

    J Craniofac Surg · 2021 · PMID 33770036

    DOI 10.1097/scs.0000000000007629Record and abstract

Excluded 90 records. Narrative review or commentary without a verified systematic selection method: 32. No direct eye examination or ocular adverse event report around hyperbaric oxygen exposure: 17. No abstract to verify population and methods: 3. Animal or cell original research first published before 2024: 33. Diving or occupational exposure rather than a hyperbaric oxygen chamber study: 3. Hyperbaric oxygen use not confirmed in the abstract: 2.

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TITLE_ABS:("hyperbaric oxygen" OR HBOT) AND TITLE_ABS:(cataract OR ocular OR ophthalm* OR myopia) AND (SRC:MED OR SRC:PMC) AND FIRST_PDATE:[* TO 2026-10-29]

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Frequently asked questions

Which eye examinations were recorded?

Reports used acuity, visual fields, refraction, lens and corneal assessment, fundus angiography, OCT and electroretinography. Populations and examination timing differ by report.

Did every paper enroll people with eye disease?

No. Alongside retinal and optic nerve cases, the list includes eye examinations and adverse event records such as myopia in people receiving hyperbaric oxygen for other conditions.

How are case reports and comparative studies distinguished?

Case and observational reports, randomized trials, other comparisons and systematic reviews are grouped separately. The same people or original studies can appear in multiple reports and reviews.