How has hyperbaric oxygen been studied with the heart?
159 papers. Randomized human trials: 15. Other comparative human studies: 18. Human observational studies and case reports: 109. Systematic reviews and meta analyses: 10. Animal studies: 6. Cell studies: 1.
Europe PMC MED and PMC title and abstract results were screened. Human research and systematic reviews containing human research have no lower publication year limit through 29 October 2026. Animal and cell original studies require a first publication date from 2024 onward. This abstract screened inventory covers the query results and is not a systematic review of all relevant literature. Counts refer to reports, with possible overlap of participants or studies across follow up reports and reviews. Groups are ordered by first publication date, newest first. Direct cardiac function, biomarker and cardiac event records are included, with other conditions and poisoning populations identified in each entry.
Checked 2026-10-29 · 442 records searched
Randomized human trials15
Fourteen healthy young men underwent randomized crossover comparisons of 60 minutes of 100% oxygen at 1.3 atmospheres and seated rest using heart rate variability, cardiac and pulmonary function and exercise oxygen uptake.
J Physiol Anthropol · 2025 · PMID 40676637
Sixty three adults older than 64 were randomized to hyperbaric oxygen or control, comparing 60 sessions of 90 minutes at 2 atmospheres over 12 weeks using maximal oxygen consumption, cardiac MRI perfusion and lung function.
BMC Geriatr · 2024 · PMID 38961397
Sixty adults with symptoms lasting at least three months after COVID were randomized to 40 hyperbaric oxygen or sham sessions; echocardiography measured left ventricular strain before and after exposure.
Sci Rep · 2023 · PMID 37301934
Seventy two carbon monoxide patients were randomized equally to additional Rhodiola or no Rhodiola; both groups received hyperbaric oxygen and medication, with endothelial and inflammatory markers and brain imaging measured.
Pak J Med Sci · 2021 · PMID 34712282
Twenty four people after coronary intervention for myocardial infarction were randomized to hyperbaric oxygen or control, comparing cardiac SPECT perfusion and ejection fraction at baseline and six weeks.
Cardiovasc Revasc Med · 2020 · PMID 32807666
One hundred twenty three severe carbon monoxide patients were randomized by additional ulinastatin use alongside usual care including hyperbaric oxygen, with ECG, BNP, troponin and myocardial enzymes followed.
Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi · 2018 · PMID 29699021
Forty nine coronary bypass patients were randomized to five days of preoperative hyperbaric oxygen or control, measuring troponin, neural biomarkers and postoperative data separately for operations with and without cardiopulmonary bypass.
J Cardiothorac Vasc Anesth · 2011 · PMID 21868252
A secondary analysis of a randomized coronary bypass trial with 41 hyperbaric oxygen and 40 control patients assessed preoperative oxygen at 2.4 atmospheres and eNOS and HSP72 in right atrial tissue.
Undersea Hyperb Med · 2011 · PMID 21721351
Eighty one coronary bypass patients were randomized to preoperative oxygen at 2.4 atmospheres or control, measuring pulmonary artery catheter hemodynamics, ventricular work, troponin and complications.
Cardiovasc Revasc Med · 2010 · PMID 20129356
A randomized controlled study in 38 diabetic foot patients compared 23 hyperbaric oxygen recipients and 15 controls, measuring daily five minute ECG heart rate variability over 20 sessions of 90 minutes at 202.65 kPa.
Diabet Med · 2006 · PMID 16620263
Seventy four patients with a first myocardial infarction were randomized to hyperbaric oxygen with streptokinase or streptokinase alone, comparing left ventricular volumes and ejection fraction on day one and at three weeks.
Am Heart J · 2004 · PMID 15459609
A diastolic function report from a randomized trial of 74 first infarction patients compared thrombolysis with and without 60 minutes of oxygen at 2 atmospheres, using repeated echocardiography through day 42.
Am Heart J · 2004 · PMID 15215810
A multicenter randomized trial analyzed 112 acute myocardial infarction patients receiving thrombolysis alone or with hyperbaric oxygen and recorded CPK, pain, ejection fraction and mortality.
Cardiology · 1998 · PMID 9778551
A randomized pilot trial analyzed 66 acute myocardial infarction patients assigned to thrombolysis alone or with hyperbaric oxygen, recording CPK, ECG, ejection fraction, pain and mortality.
Am Heart J · 1997 · PMID 9327714
Thirty four acute ischemic stroke patients were randomized to hyperbaric oxygen or air; 27 completed the course. Neurological function and reasons for discontinuation including myocardial infarction were recorded.
Stroke · 1995 · PMID 7631339
Other comparative human studies18
A retrospective study compared 169 normobaric oxygen and 103 hyperbaric oxygen recipients among 272 adults exposed to carbon monoxide, examining troponin, CKMB, ECG and selection factors.
Int J Gen Med · 2026 · PMID 42293118
A retrospective comparison of hyperbaric oxygen alongside usual care versus usual care after heatstroke assessed myocardial enzymes, organ and daily function at baseline, two and four weeks; sample size was unstated.
Heliyon · 2024 · PMID 38545173
Records of 83 children exposed to carbon monoxide compared selection of hyperbaric and normobaric oxygen using ECG, myocardial ischemia assessment, lactate and exposure duration.
Turk Arch Pediatr · 2023 · PMID 37144261
Taiwanese data from 5,312 chronic osteomyelitis patients were reviewed, comparing 265 hyperbaric oxygen recipients and 994 controls after propensity matching for myocardial infarction, stroke admissions and mortality.
J Infect Public Health · 2023 · PMID 36940497
Fifteen healthy volunteers underwent five normobaric and hyperbaric oxygen conditions, with microcirculation, vascular occlusion testing, transthoracic echocardiography and blood pressure measured.
Diving Hyperb Med · 2022 · PMID 36525683
Twenty patients with carbon monoxide exposure and myocardial injury received 40 sessions of 90 minutes at 2.4 atmospheres and were compared with 20 healthy controls using HO1 expression, pulmonary artery pressure and six minute walking.
Cell Mol Biol (Noisy-le-grand) · 2022 · PMID 36227680
Thirty two people with diabetic foot and metabolic syndrome received eight to ten sessions at 1.7 or 1.8 atmospheres and were compared with 20 healthy controls using ventricular diastolic function and arterial and venous oxygen measures.
Pol Merkur Lekarski · 2021 · PMID 33713090
Taiwanese records compared myocardial infarction occurrence in 7,278 hyperbaric oxygen recipients and 18,459 nonrecipients after carbon monoxide exposure, incorporating age, sex and underlying conditions.
Cardiovasc Toxicol · 2020 · PMID 31729615
Seventy carbon monoxide patients were compared between hyperbaric oxygen and extracorporeal membrane oxygenation groups of 35 each alongside 30 healthy controls, measuring myocardial enzymes, miR30a and complications.
Exp Ther Med · 2020 · PMID 32742349
A retrospective comparison of 115 coronary stent recipients included 55 hyperbaric oxygen recipients and 60 controls, measuring brachial artery dilation, nitric oxide, endothelin and inflammatory markers.
Undersea Hyperb Med · 2019 · PMID 31051059
A retrospective study compared 48 hyperbaric oxygen recipients and 50 usual care patients among 98 people with slow coronary flow using myocardial perfusion imaging, filling indices and ventricular volumes over four weeks.
Undersea Hyperb Med · 2018 · PMID 30241119
A retrospective comparison of 115 coronary patients with drug eluting stents included 55 hyperbaric oxygen recipients and 60 controls, measuring myocardial SPECT and endothelial and inflammatory markers.
Ann Clin Lab Sci · 2018 · PMID 29678841
Thirty two healthy men underwent six hours of water immersion with air, chamber oxygen or immersion with oxygen at 1.35 atmospheres, with tilt testing, cardiac output, blood pressure, stroke volume and vascular resistance measured.
Physiol Rep · 2016 · PMID 28604343
Ten healthy volunteers underwent air and oxygen conditions at matched pressures, with arterial and pulmonary artery catheter measurements of pressure, cardiac output, blood gases and oxygen extraction.
J Appl Physiol (1985) · 2009 · PMID 19407250
Records of 42 patients with Fournier gangrene compared complications including myocardial infarction and hospital course in 16 receiving surgery and antibiotics and 26 also receiving hyperbaric oxygen.
J Urol · 2005 · PMID 15879795
A trial compared 24 hyperbaric oxygen recipients with 37 nonrecipients after coronary intervention for infarction or unstable angina, recording major cardiac events over eight months; randomization was unstated.
Am J Cardiol · 2004 · PMID 15194029
Ten professional divers underwent oxygen and air conditions at 2.5 ATA, with ECG measurements of heart rate variability, cardiac conduction and arrhythmias.
Acta Physiol Scand · 2000 · PMID 10971221
A comparative study of 340 patients receiving hyperbaric oxygen and 185 receiving medication alone after intoxication or during withdrawal assessed clinical status, central hemodynamics and myocardial status.
Anesteziol Reanimatol · 1995 · PMID 7653862
Human observational studies and case reports109
An observational study measured ECG and heart rate variability before hyperbaric oxygen in eight divers with neurological decompression sickness, describing autonomic status before exposure.
Front Physiol · 2026 · PMID 42359250
An interim prospective report followed 100 adults with ischemic cardiomyopathy receiving external counterpulsation, hyperbaric oxygen and medication; echocardiography, cardiac biomarkers, walking and admissions were recorded over six months.
J Card Fail · 2026 · PMID 42102952
A case report concerned one man with gas embolism after midline catheter disconnection; echography identified gas in cardiac chambers and the course after hyperbaric oxygen and supportive care was recorded.
SAGE Open Med Case Rep · 2026 · PMID 42037642
A case report followed chest pain in one woman receiving hyperbaric oxygen after carbon monoxide exposure, documenting cardiac biomarkers, coronary angiographic dissection and a six month course.
Turk Kardiyol Dern Ars · 2026 · PMID 41628054
A case series followed four patients receiving hyperbaric oxygen after severe carbon monoxide exposure, recording echocardiography, ECG, troponin, thrombi and subsequent course.
Undersea Hyperb Med · 2026 · PMID 42365948
Cardiac, abdominal and thoracic ultrasound images were recorded at different pressures in one human subject in a chamber, evaluating operation and image acquisition with four portable machines.
Undersea Hyperb Med · 2026 · PMID 41979525
Records of 288 people receiving hyperbaric oxygen after carbon monoxide exposure were compared by consciousness status, recording myocardial injury, shock, ventilation and early symptoms.
Int J Emerg Med · 2025 · PMID 41436924
A ten question survey received responses from 14 of 15 hyperbaric units in Australia and New Zealand, examining chamber cardiac arrest and defibrillation experience and procedures.
Diving Hyperb Med · 2025 · PMID 41364857
Prospective data from 82 adults exposed to carbon monoxide were analyzed for hyperbaric oxygen selection, myocardial injury and blood biomarkers; 26.6% received hyperbaric oxygen.
Intern Emerg Med · 2025 · PMID 41201774
An observational report followed 25 thoracic trauma patients receiving two hour oxygen sessions at 2.4 atmospheres, recording cardiac and respiratory events including chest pain and arrhythmias over a median 11 sessions.
Ulus Travma Acil Cerrahi Derg · 2025 · PMID 40910705
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One man with hyperkalemia and carbon monoxide exposure received medication in a hyperbaric oxygen environment followed by hemodialysis; ECG, arrhythmia, electrolytes and the four week course were recorded.
Medicine (Baltimore) · 2025 · PMID 40587713
Heart rate variability during and after hyperbaric oxygen was analyzed in one diver with neurological decompression sickness and bradycardia using continuous monitoring and two 24 hour Holter recordings.
Front Physiol · 2025 · PMID 40365084
Records of 502 people exposed to carbon monoxide analyzed hyperbaric oxygen use, delayed neurological findings and myocardial injury using clinical and laboratory variables in multivariable models.
J Chin Med Assoc · 2025 · PMID 39815402
One woman received hyperbaric oxygen after coronary air embolism and myocardial infarction following lung biopsy; hemodynamics, imaging, ECG and subsequent pneumothorax were recorded.
Diving Hyperb Med · 2024 · PMID 39288930
A woman with cardiogenic shock after carbon monoxide exposure received hyperbaric oxygen; troponin, ECG, echocardiographic ejection fraction and intensive care course were recorded.
Ann Burns Fire Disasters · 2024 · PMID 38974793
One man with perineal infection and multiple organ abnormalities received surgery, antibiotics and hyperbaric oxygen; myocardial necrosis, thrombosis and other complications were recorded.
Clin Case Rep · 2024 · PMID 38707606
A retrospective study recorded consciousness, blood gases, left ventricular ejection fraction and volumes in 111 patients receiving hyperbaric oxygen with chamber ventilation after difficulty separating from ventilation following tracheostomy.
Biomed Eng Online · 2024 · PMID 38454458
A retrospective study followed 23 heart failure patients receiving an average 39 sessions at 2.0 or 2.4 atmospheres at two centers, recording ejection fraction, BNP, pulmonary edema symptoms and fluid management.
PLoS One · 2024 · PMID 38330042
A case report described hyperbaric oxygen exposure and survival course in one 31 year old patient after cardiac arrest and resuscitation following carbon monoxide exposure.
Undersea Hyperb Med · 2024 · PMID 38615351
A patient with impaired consciousness after carbon monoxide exposure received medication and hyperbaric oxygen; ECG T waves, brain MRI and clinical course were recorded.
Undersea Hyperb Med · 2024 · PMID 39348516
A prospective observation of 155 people with carbon monoxide exposure and elevated troponin analyzed cardiac MRI, echocardiography, lactate and time from rescue to hyperbaric oxygen.
Diagnostics (Basel) · 2023 · PMID 38201369
One man exposed to carbon monoxide underwent hyperbaric oxygen followed by coronary angiography; ECG, troponin and right coronary artery findings were recorded.
Cureus · 2023 · PMID 38283462
High sensitivity troponin T was measured before and after each of 30 hyperbaric oxygen sessions in 48 people with noncardiac conditions, observing repeated exposure and cardiac biochemistry.
Diving Hyperb Med · 2023 · PMID 37718303
A case report described pulmonary edema during the first hyperbaric oxygen session for a foot ulcer in one patient with low ejection fraction and mitral regurgitation, documenting exposure and cardiac history.
Cureus · 2023 · PMID 36909067
Troponin I, NTproBNP and ECG were compared before and after the first hyperbaric oxygen session in diabetic patients, including QT and QTc measurements; sample size was not stated in the abstract.
Undersea Hyperb Med · 2023 · PMID 38055884
A case report described resuscitation and multiple hyperbaric oxygen sessions in one diver after cardiac arrest, documenting transport, differential diagnosis and the subsequent course.
Undersea Hyperb Med · 2023 · PMID 36820807
One woman with air embolism after lung biopsy received two hyperbaric oxygen sessions and other care; arrhythmia, myocardial infarction, ECG and the three month neurological course were recorded.
Undersea Hyperb Med · 2023 · PMID 37708060
Two young male fire survivors receiving care including hyperbaric oxygen were assessed for exercise intolerance with cardiopulmonary exercise testing and exercise ECG for myocardial ischemia, with six month follow up.
BMC Cardiovasc Disord · 2022 · PMID 36575398
A retrospective study reviewed blood tests, ECG and echocardiography in 107 children exposed to carbon monoxide, recording hyperbaric oxygen use and measures including troponin and NTproBNP.
Ir J Med Sci · 2022 · PMID 36445626
Transthoracic echocardiography before and after hyperbaric oxygen examined microbubbles and structure in the right cardiac chambers of one diver with decompression sickness.
Clin Case Rep · 2022 · PMID 35441009
Records of 23 hyperbaric oxygen recipients aged at least 40 with ejection fraction at most 40% were reviewed for events including heart failure during a mean 25 sessions and within 24 hours afterward.
Diving Hyperb Med · 2021 · PMID 34547776
One seven day old boy exposed to carbon monoxide received hyperbaric oxygen; carboxyhemoglobin, cardiac markers and clinical course were recorded.
Pediatr Emerg Care · 2020 · PMID 30335685
A case report described the resuscitation course including hyperbaric oxygen in one man with air embolism and cardiac arrest after lung needle biopsy.
Rev Esp Anestesiol Reanim (Engl Ed) · 2020 · PMID 32444113
ECG before and 15 hours after hyperbaric oxygen initiation was compared in one man with syncope after carbon monoxide exposure, recording QTc and carboxyhemoglobin.
J Cardiol Cases · 2020 · PMID 32636963
One pilot with high altitude decompression sickness received hyperbaric oxygen, extracorporeal oxygenation and ventilation; heart failure, circulatory collapse, organ status and a 19 day hospital course were recorded.
Aerosp Med Hum Perform · 2020 · PMID 31980050
Echocardiography before and after 60 hyperbaric oxygen sessions in 31 people measured left ventricular ejection fraction, volumes, strain, rotation and other myocardial function indices.
Int J Cardiovasc Imaging · 2020 · PMID 31953651
A case report observed cardiac rhythm before and after hyperbaric oxygen in one patient with carbon monoxide exposure and atrial fibrillation.
Undersea Hyperb Med · 2020 · PMID 32176956
A cross sectional analysis of 67 carbon monoxide patients examined hyperbaric oxygen use, acute myocardial injury, brain imaging and blood tests, dividing participants by brain imaging findings.
Int J Environ Res Public Health · 2019 · PMID 31718107
One woman with chest pain after carbon monoxide exposure received medication and hyperbaric oxygen; serial ECG and coronary angiography were recorded.
Medicine (Baltimore) · 2019 · PMID 31008930
ECG QTc and QTc dispersion before and after hyperbaric oxygen were compared in 31 people exposed to carbon monoxide, alongside analysis of carboxyhemoglobin.
Undersea Hyperb Med · 2018 · PMID 31158934
Three gas embolism cases after peroxide ingestion, endoscopy or intrapleural medication received hyperbaric oxygen; myocardial infarction in one patient and each clinical course were recorded.
Case Rep Crit Care · 2018 · PMID 30073096
Shock after the first hyperbaric oxygen session in one woman exposed to carbon monoxide was assessed with cardiac ultrasound and right ventricular findings before and after exposure, alongside the course after thrombolytic medication.
Am J Emerg Med · 2018 · PMID 29875063
One man with cardiac injury after carbon monoxide exposure received three 120 minute sessions at 2.4 atmospheres; troponin, ECG and repeated echocardiography were recorded.
Intensive Crit Care Nurs · 2018 · PMID 29753599
A case report assessed respiratory and cardiac status with chest imaging and echocardiography after seizures and pulmonary edema during a second hyperbaric oxygen session in one man exposed to carbon monoxide.
J Med Invest · 2018 · PMID 30282875
A case report documented 44 hyperbaric oxygen sessions for a bladder radiation lesion in one patient with a left ventricular assist device, including prior mock circulation testing, power modifications and device operation.
Undersea Hyperb Med · 2018 · PMID 29571237
Hyperbaric oxygen began six days after diving in one man with unconsciousness and circulatory collapse; ventilation, cardiovascular status and the one year course were recorded.
Diving Hyperb Med · 2017 · PMID 29241237
A case report recorded the cardiac rhythm course in one young man receiving hyperbaric oxygen after carbon monoxide exposure with atrial fibrillation.
S D Med · 2017 · PMID 28806029
A retrospective analysis of 294 concentrated peroxide ingestions in US poison center records examined hyperbaric oxygen timing and events including ECG findings, troponin and cardiac emboli.
Ann Emerg Med · 2017 · PMID 28153539
A review of 67 gas embolism cases over 25 years recorded cardiac gas location, cardiac arrest, procedures and course; 21% received hyperbaric oxygen.
Diagnostics (Basel) · 2017 · PMID 28106717
A prospective observation of 288 children hospitalized after carbon monoxide exposure included two hyperbaric oxygen recipients, recording ECG, myocardial enzymes, troponin and lactate.
Pediatr Emerg Care · 2016 · PMID 26181501
One man exposed to hydrogen sulfide received ventilation, hyperbaric oxygen and medication; myocardial infarction, ventricular arrhythmia, left ventricular function and course were recorded.
Cardiology · 2016 · PMID 27193372
A two person case series described hyperbaric oxygen within hours after carbon monoxide exposure with myocardial infarction, documenting ECG, echocardiography and coronary assessment.
Undersea Hyperb Med · 2016 · PMID 27000015
A prospective US hyperbaric center reporting system analyzed 264 carbon monoxide exposures involving portable generators, recording demographics, exposure location and findings including cardiac ischemia.
J Emerg Med · 2015 · PMID 26032763
Records of 261 carbon monoxide patients, 18.8% receiving hyperbaric oxygen, were analyzed for myocardial infarction, shock, multiple organ findings and discharge status.
PLoS One · 2015 · PMID 25745854
A case report described baseline cardiac status and acute pulmonary edema after hyperbaric oxygen for a foot lesion in one man with systolic heart failure and diabetes.
Oxf Med Case Reports · 2015 · PMID 25988073
A report combined a European survey of equipment use inside hyperbaric chambers with defibrillation and implanted device conditions; the number of responding centers was not stated in the abstract.
Diving Hyperb Med · 2014 · PMID 25596835
A prospective observation of 325 children exposed to carbon monoxide recorded ECG, myocardial enzymes, neurological findings and blood gases; 23.7% received hyperbaric oxygen.
Turk Pediatri Ars · 2014 · PMID 26078683
A retrospective review assessed 189 of 276 hyperbaric oxygen recipients with follow up after radiation tissue injury, recording complications including myocardial infarction.
Asia Pac J Clin Oncol · 2014 · PMID 25382755
One man with air embolism during pacemaker lead extraction received hyperbaric oxygen; transesophageal echocardiography, coronary angiography, ECG and brain MRI were recorded.
Heart Lung Circ · 2014 · PMID 25287448
One patient with acute coronary syndrome and left ventricular dysfunction after carbon monoxide exposure received hyperbaric oxygen; coronary angiography, ECG and cardiac biomarkers were recorded.
Ann Cardiol Angeiol (Paris) · 2014 · PMID 25261170
Eleven patients and nine staff underwent transthoracic echocardiography before and during oxygen at 243 kPa; two independent readers assessed cardiac output, heart rate, stroke volume and chamber volumes.
Diving Hyperb Med · 2014 · PMID 25311320
One patient exposed to carbon monoxide while lighting hookah coals received hyperbaric oxygen; carboxyhemoglobin and ischemic ECG findings were recorded.
J Med Toxicol · 2014 · PMID 24381126
Cardiac output before, during and after 90 minutes of 100% oxygen at 284 kPa was measured with transesophageal Doppler in seven patients with necrotizing fasciitis and sepsis.
Diving Hyperb Med · 2013 · PMID 23508657
A case report recorded cardiac arrest after a second hyperbaric oxygen session for intestinal obstruction in one man, documenting tension pneumothorax, thoracic drainage and resuscitation.
Masui · 2013 · PMID 23479918
One woman exposed to carbon monoxide received heparin with hyperbaric oxygen; cardiac enzymes, troponin and repeated echocardiography documented a right atrial thrombus.
Hum Exp Toxicol · 2013 · PMID 23357963
Four patients with severe carbon monoxide exposure received three hyperbaric oxygen sessions and 24 hours of hypothermia; organ status including cardiac function and neurological status at discharge were recorded.
Undersea Hyperb Med · 2013 · PMID 23397870
One woman with venous gas embolism and cardiac arrest after laparoscopic surgery received resuscitation followed by hyperbaric oxygen; echocardiography, catheter gas aspiration and recurrent arrest were recorded.
Scand J Trauma Resusc Emerg Med · 2012 · PMID 22862957
One woman with cardiac arrest and right cardiac gas after laparoscopic surgery received resuscitation, catheter aspiration and hyperbaric oxygen; ultrasound and the 14 day hospital course were recorded.
Surg Laparosc Endosc Percutan Tech · 2012 · PMID 22678344
One commercial diver with unconsciousness received hyperbaric oxygen before contaminated air exposure was identified; carboxyhemoglobin, cardiac injury and neurological course were recorded.
Undersea Hyperb Med · 2012 · PMID 22530451
A retrospective series of six people with calcific uremic arteriolopathy documented multiple combined approaches including hyperbaric oxygen and myocardial infarction among causes of death.
Int J Nephrol · 2012 · PMID 22518312
A report described experience combining hyperbaric oxygen with prehospital resuscitation in diving field cases involving trauma and cardiopulmonary arrest; case counts were not stated in the abstract.
Surg Technol Int · 2011 · PMID 22504971
A case report recorded the course after resuscitation and neurological status in one patient receiving hyperbaric oxygen and hypothermia after hydrogen sulfide exposure with cardiac arrest.
Respir Care · 2011 · PMID 22004989
One man with acute coronary syndrome and cerebral embolism after diving received hyperbaric oxygen; subsequent coronary angiography and clinical course were recorded.
J Cardiol Cases · 2010 · PMID 30532827
Two term newborns with hypoxic encephalopathy received hyperbaric oxygen; clinical status and total and myocardial CPK were recorded through 24 hours after the first exposure.
Diving Hyperb Med · 2010 · PMID 23111939
A case report of a 12 day old girl with cardiac arrest during laparoscopy recorded cardiac rhythm, CT, MRI and the course around resuscitation and hyperbaric oxygen.
Can J Anaesth · 2010 · PMID 20431981
One woman with systemic gas embolism during hysteroscopy received hyperbaric oxygen and other care; bilateral cardiac bubbles on echocardiography, troponin and brain imaging were recorded.
Undersea Hyperb Med · 2010 · PMID 20462140
A case report documented cardiac arrest during decompression after hyperbaric oxygen in one severe carbon monoxide patient, including acid base status, electrolytes, resuscitation and subsequent resumed exposure.
Anaesthesist · 2009 · PMID 19562396
Records of 81 carbon monoxide patients receiving ventilation and oxygen at 2.5 or 2.8 atmospheres were reviewed for emergency myocardial injury, cardiac enzymes, troponin and discharge status.
Pulm Pharmacol Ther · 2009 · PMID 19393326
One man with myocarditis after carbon monoxide exposure received hyperbaric oxygen; coronary angiography, cardiac MRI and carboxyhemoglobin were recorded.
Int J Cardiol · 2009 · PMID 19359056
Thirty one first infarction patients received thrombolysis and one hour of oxygen at 2 atmospheres within 24 hours; echocardiographic wall motion before and after exposure was compared with dobutamine stress testing.
Gen Physiol Biophys · 2009 · PMID 19893090
A case report of a 17 year old woman with carbon monoxide exposure and ST depression recorded blood gases, ECG and the clinical course around ten hyperbaric oxygen sessions.
Bratisl Lek Listy · 2009 · PMID 20120442
A detailed report of one man among six perineal infection cases documented heart failure, atrial fibrillation and pulmonary embolism during care combining surgery, medication and hyperbaric oxygen.
Vojnosanit Pregl · 2008 · PMID 19024125
Twenty five diabetic patients were prospectively enrolled for NTproBNP, heart rate and blood pressure measurements before and after hyperbaric oxygen, with baseline echocardiography.
Clin Invest Med · 2008 · PMID 18980711
A case report described hyperbaric oxygen, organ status and a fatal course in one man with cardiac arrest following air injection during eye surgery.
Ann Fr Anesth Reanim · 2008 · PMID 18824322
One patient with gas embolism and arrhythmia after peroxide wound irrigation received initial care followed by hyperbaric oxygen; oxygen saturation, exhaled carbon dioxide and cardiac rhythm were recorded.
Ann Fr Anesth Reanim · 2008 · PMID 18755568
Thirty diabetic patients underwent 12 lead ECG before and after ten hyperbaric oxygen sessions over two weeks, comparing QT and heart rate corrected QTc dispersion.
Tohoku J Exp Med · 2008 · PMID 18509242
A case report of an 82 year old woman with cardiac arrest and air embolism during biliary endoscopy recorded CT, hemodynamics and the hospital course around resuscitation and hyperbaric oxygen.
Ann Fr Anesth Reanim · 2008 · PMID 18313255
Thirty diabetic patients underwent Doppler echocardiography before the first and after the tenth hyperbaric oxygen session, measuring ventricular diastolic filling and tissue Doppler indices.
Tohoku J Exp Med · 2008 · PMID 18323697
One patient with coronary and cerebral air embolism after lung needle biopsy received hyperbaric oxygen and medication; myocardial infarction, atrial fibrillation and CT gas findings were recorded.
Tex Heart Inst J · 2008 · PMID 19156246
Eight healthy volunteers received two 45 minute oxygen periods separated by five minutes of air at 2.5 atmospheres; BNP was measured at baseline, completion and five hours after baseline.
Aviat Space Environ Med · 2007 · PMID 17225483
A prospective cohort followed 230 adults receiving hyperbaric oxygen after carbon monoxide exposure, assessing myocardial injury with ECG, troponin and CKMB and recording mortality over a median 7.6 years.
JAMA · 2006 · PMID 16434630
A five year record review of 12 patients with carbon monoxide exposure recorded complications including myocardial ischemia and hospital course. One received hyperbaric oxygen; the abstract did not separately report that person's cardiac measures.
Ann Acad Med Singap · 2005 · PMID 16382246
Cardiovascular records of 230 people receiving hyperbaric oxygen after moderate or severe carbon monoxide exposure were reviewed for ECG, CKMB, troponin and hospital mortality.
J Am Coll Cardiol · 2005 · PMID 15862427
A case report of a 21 year old man with coronary and cerebral air embolism recorded ECG, echocardiography and the clinical course around resuscitation and hyperbaric oxygen.
J Emerg Med · 2003 · PMID 12865105
Ten intensive care patients underwent repeated pulmonary artery catheter measurements of cardiac output, vascular resistance and oxygen transport before and one and two hours after 50 minutes of oxygen at 2.2 ATA.
Acta Anaesthesiol Scand · 2003 · PMID 12699512
A case series recorded hyperbaric oxygen associated pulmonary edema in three people with cardiac disease and reduced left ventricular ejection fraction, including histories of diabetes or aortic stenosis and clinical course.
Chest · 2001 · PMID 11591590
Records of 18 patients receiving hyperbaric oxygen after resuscitation from carbon monoxide associated cardiac arrest described cardiac rhythm, exposure, resuscitation and hospital survival, with a separate survey of medical directors.
Ann Emerg Med · 2001 · PMID 11423810
Records of 150 children receiving hyperbaric oxygen after carbon monoxide exposure were compared by smoke exposure, examining field cardiac and respiratory arrest, admission status and mortality.
Pediatr Emerg Care · 2000 · PMID 10888449
A case report of a 42 year old woman with myocardial infarction findings after carbon monoxide exposure recorded hyperbaric oxygen use, CK, ECG, echocardiography and coronary angiography.
Zhonghua Yi Xue Za Zhi (Taipei) · 1996 · PMID 8768384
Twenty four patients within one week of acute myocardial infarction underwent echocardiography around hyperbaric oxygen, compared with exercise thallium SPECT assessments of myocardial viability.
Am Heart J · 1992 · PMID 1442480
A record review of 14 women with ergotamine associated limb ischemia described peripheral pressures, ECG and liver function across an earlier hyperbaric oxygen period and a later nitroglycerin period. The hyperbaric subgroup size was not stated in the abstract.
Ugeskr Laeger · 1989 · PMID 2773132
A ten year retrospective review of 297 carbon monoxide patients receiving hyperbaric oxygen examined timing of cardiac arrest, myocardial infarction, arrhythmias, hypotension and other events before and during exposure.
Ann Emerg Med · 1989 · PMID 2729687
A case series of five patients with carbon monoxide exposure examined ECG records around hyperbaric oxygen, observing heart rate, atrial fibrillation and ventricular repolarization.
Cardiologia · 1989 · PMID 2758446
A record review of ten burn patients with carbon monoxide exposure receiving hyperbaric oxygen examined arrhythmias, volume status, respiration, other complications and hospital survival.
J Burn Care Rehabil · 1988 · PMID 3417718
A record review of patients receiving hyperbaric oxygen for head and neck disease examined complications including myocardial infarction, seizure and stroke. The total sample size was not stated in the abstract.
Otolaryngol Head Neck Surg · 1986 · PMID 3086814
One case of severe decompression sickness with premature ventricular contractions documented lidocaine infusion and the course during hyperbaric recompression. Continuous cardiac monitoring was unavailable.
Ann Emerg Med · 1980 · PMID 7436069
Thirty two ischemic stroke patients underwent repeated central hemodynamic measurements before, immediately after and two to three hours after hyperbaric oxygen. Three hundred tetrapolar rheograms assessed cardiac output, blood pressure and heart rate.
Zh Vopr Neirokhir Im N N Burdenko · 1980 · PMID 7435068
Fifty patients with emphysema after bronchitis underwent hyperbaric oxygen and examinations of respiratory function, blood oxygenation, cardiac function and other organ functions.
Minerva Med · 1976 · PMID 934539
A case report of a 22 year old woman with pregnancy associated cardiomyopathy and heart failure recorded care including cesarean delivery in a hyperbaric chamber, cardiopulmonary and neurological course, and autopsy findings.
Br Med J · 1968 · PMID 5693910
Systematic reviews and meta analyses10
A qualitative review searched four databases and included five clinical studies with 431 adults, examining hyperbaric oxygen and myocardial injury, inflammatory and endothelial biomarkers.
Cureus · 2026 · PMID 42093774
A scoping review selected 33 publications from four databases concerning defibrillation during hyperbaric oxygen; four reports described five actual patients, alongside equipment and procedural conditions.
Diving Hyperb Med · 2025 · PMID 41364865
A meta analysis included three observational studies with 195 coronary disease patients after revascularization, examining left ventricular ejection fraction and volumes with and without hyperbaric oxygen.
Br J Cardiol · 2025 · PMID 42422150
A review examined 41 publications from four databases and additional sources concerning resuscitation during hyperbaric oxygen; 18 reports described resuscitation or defibrillation in 22 patients.
Scand J Trauma Resusc Emerg Med · 2023 · PMID 37872558
A meta analysis of retrospective comparisons included 49,152 people with necrotizing soft tissue infection, comparing 1,448 hyperbaric oxygen recipients and 47,704 controls for complications including myocardial infarction, surgery and mortality.
World J Emerg Surg · 2023 · PMID 36966323
A systematic review combined published cases and poison database records for 126 peroxide exposures, including 54 hyperbaric oxygen recipients, recording gas embolism timing with myocardial infarction and obstructive shock among events.
Clin Toxicol (Phila) · 2022 · PMID 36440836
A systematic search reviewed 83 reports involving 97 people with systemic air embolism after lung biopsy, including 34 hyperbaric oxygen recipients, documenting cardiac arrest, presentation, procedures and course.
Acta Radiol Open · 2022 · PMID 35770135
A 2015 systematic review of six randomized trials with 665 people with acute coronary syndromes compared regimens with and without hyperbaric oxygen for cardiac events, mortality and adverse events, updating an earlier review.
Cochrane Database Syst Rev · 2015 · PMID 26202854
A 2011 systematic review of six randomized trials with 665 acute coronary syndrome patients examined myocardial enzymes, ejection fraction, cardiac events and mortality in regimens with and without hyperbaric oxygen.
Cochrane Database Syst Rev · 2011 · PMID 21833950
A 2005 systematic review of four randomized trials with 462 acute coronary syndrome patients examined cardiac events, arrhythmias, mortality and adverse events with and without hyperbaric oxygen.
Cochrane Database Syst Rev · 2005 · PMID 15846734
Animal studies6
Rats exposed to carbon monoxide were compared with and without hyperbaric oxygen using echocardiography, cardiac tissue, biochemistry and cardiac and serum extracellular vesicle proteomics; sample size was not stated in the abstract.
Mol Med · 2026 · PMID 42393509
Thirty male rats in five groups underwent aortic occlusion and reperfusion with colchicine and oxygen at 2.5 atmospheres alone or together; ECG, cardiac tissue and oxidative and inflammatory markers were measured.
Fundam Clin Pharmacol · 2026 · PMID 42363694
Hyperbaric oxygen was examined in mice exposed to carbon monoxide and human cardiac fibroblasts using cardiac tissue, collagen, cell proliferation, oxidative measures and signaling proteins; sample size was not stated in the abstract.
Eur J Pharmacol · 2026 · PMID 42162689
One macaw with bradycardia after plant ingestion received multiple medications, supplemental oxygen and hyperbaric oxygen; blood tests, circulatory status and owner reports three years later were recorded.
J Avian Med Surg · 2026 · PMID 41926281
Piglets underwent 240 minutes of hyperbaric hyperoxic ventilation; respiratory chain, ATP synthase and proteomic measures were compared between two cardiac mitochondrial populations, with sample size unstated.
PNAS Nexus · 2024 · PMID 38881840
A rat coronary ligation model examined prior hyperbaric oxygen with Mst1 gene manipulation using cardiac function, infarct area, histology and oxidative and inflammatory markers; sample size was not stated in the abstract.
Mol Biotechnol · 2024 · PMID 38393629
Cell studies1
HL1 cardiomyocytes were exposed to oxygen at 3 atmospheres for two or six hours; oxidants, genes, mitochondrial respiration, ATP and spontaneous beating were measured, with sample size unstated in the abstract.
J Appl Physiol (1985) · 2025 · PMID 40402925
Excluded 283 records. Wildlife veterinary case: 1. No direct cardiac or vascular measurement or cardiac event report: 70. Narrative review, commentary or guidance without a verified systematic selection method: 81. Equipment, simulation or training proposal without direct observation of an eligible biological subject: 5. Hyperbaric oxygen chamber exposure not verified in the abstract: 39. Animal or cell original research first published before 2024: 60. No abstract to verify population and methods: 27.
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TITLE_ABS:("hyperbaric oxygen" OR HBOT) AND TITLE_ABS:(cardiac OR myocardial OR "heart failure" OR "cardiovascular aging" OR "cardiovascular ageing") AND (SRC:MED OR SRC:PMC) AND FIRST_PDATE:[* TO 2026-10-29]
Search Europe PMCFrequently asked questions
Which cardiac measures were recorded?
Reports used echocardiographic ejection fraction and strain, ECG and heart rate variability, troponin, BNP and myocardial enzymes, perfusion imaging and cardiac events.
Are diabetic foot or cardiac surgery papers included?
They are included when cardiac function, biomarkers or cardiac events were recorded directly. Reports limited to wounds, hearing or brain examinations are excluded from this page.
How are human studies separated from animal and cell studies?
Human reports are grouped by design, with animal and cell original research in separate groups. Animal and cell reports require a first publication date from 2024 onward; follow up reports can share samples.